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. 2009 Mar 2;27(11):1844–1849. doi: 10.1200/JCO.2008.17.0795

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© 2009 by American Society of Clinical Oncology

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Fig 3. — Overall survival (OS) based on the percentage of smudge cells on blood smear. (A) Kaplan-Meier estimates of OS based on the percentage of smudge cells in the entire cohort. The 10-year survival rate was 50% v 80% for patients with smudge cell percentage ≤ 30% v more than 30%, respectively (P = .015). (B) Kaplan-Meier estimates of OS based on the percentage of smudge cells in patients with Rai stage 0 and I disease only. The 10-year survival rate was 61% v 84% for patients with smudge cell percentage ≤ 30% v more than 30%, respectively (P = .033). (C) Kaplan-Meier estimates of OS based on smudge cell percentage and CD38 expression. The 10-year survival of patients with CD38⁺ disease and less than 30% smudge cells was only 13% compared with 58%, 72%, and 85% for patients with CD38⁺ disease and ≥ 30% smudge cells, CD38^– disease and less than 30% smudge cells, and CD38^– disease and ≥ 30% smudge cells, respectively (P < .001).