Table 1.
Patient Characteristics
| Characteristic | No. of Patients (N = 108) | % |
|---|---|---|
| Age, years | ||
| Median | 63 | |
| Range | 36-83 | |
| Male | 73 | 68 |
| Rai stage | ||
| 0 | 53 | 49 |
| I | 34 | 31 |
| II | 13 | 12 |
| III | 2 | 2 |
| IV | 6 | 6 |
| Zap70 ≥ 20% | 63 | 58 |
| IgVH unmutated* | 41 | 46 |
| CD38 ≥ 30% | 33 | 30 |
| FISH | ||
| del 13q14.2 | 41 | 38 |
| Normal | 30 | 28 |
| Trisomy 12 | 18 | 17 |
| del 11q22.3 | 7 | 6 |
| del 17p13.1 | 6 | 6 |
| Other | 3 | 3 |
Abbreviations: FISH, fluorescence in situ hybridization; IgVH, immunoglobulin heavy chain.
IgVH gene mutation status was attempted for all patients but classifiable for 89 patients.