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. 2009 Mar 2;27(11):1844–1849. doi: 10.1200/JCO.2008.17.0795

Table 2.

Univariate Analysis for Overall Survival

Variable HR 95% CI P
Smudge cell percentage: ≤ 30% 2.1 1.1 to 4.1 .018
FISH: 11q- or 17p- 1.9 0.9 to 4.1 .11
IgVH unmutated 1.8 0.9 to 3.7 .071
Zap70: ≥ 20% 1.9 1.1 to 4.4 .017
CD38: ≥ 30% 3.4 1.8 to 6.2 < .001
Rai stage: III or IV 4.8 1.9 to 11.8 < .001
Age: > 60 years 1.8 0.9 to 3.6 .083
Sex: male 1.2 0.6 to 2.5 .51

Abbreviations: HR, hazard ratio; FISH, fluorescence in situ hybridization; IgVH, immunoglobulin heavy chain.