Table A1.
Characteristic | Slides Reviewed (n = 108) |
Slides Not Available (n = 51) |
P | ||
---|---|---|---|---|---|
No. of Patients | % | No. of Patients | % | ||
Age, years | .65 | ||||
Median | 63 | 65 | |||
Range | 36-83 | 41-87 | |||
Male | 73 | 68 | 39 | 76 | |
Rai stage | .44 | ||||
0 | 53 | 49 | 31 | 60 | |
I | 34 | 31 | 14 | 27 | |
II | 13 | 12 | 5 | 10 | |
III | 2 | 2 | 0 | 0 | |
IV | 6 | 6 | 1 | 2 | |
Lymphocyte count, ×109/L | .54 | ||||
Median | 17.8 | 16.9 | |||
Range | 2.0-278.4 | 5.1-167 | |||
Zap70 ≥ 20% | 63 | 58 | 20 | 40 | .04 |
IgVH unmutated* | 41 | 46 | 15 | 47 | .84 |
CD38 ≥ 30% | 33 | 30 | 13 | 26 | .45 |
FISH | .66 | ||||
del 13q14.2 | 41 | 38 | 30 | 58 | |
Normal | 30 | 28 | 9 | 18 | |
Trisomy 12 | 18 | 17 | 5 | 10 | |
del 11q22.3 | 7 | 6 | 5 | 10 | |
del 17p13.1 | 6 | 6 | 1 | 2 | |
Other | 3 | 3 | 1 | 2 |
Abbreviations: FISH, fluorescence in situ hybridization; IgVH, immunoglobulin heavy chain.
IgVH gene mutation status was attempted for all patients but classifiable for 126 patients.