Table 3.
Selected genes up-regulated in Rac1+/− mouse ECs. Genes are categorized by the GO annotation.
| Symbol | Gene name | Fold |
|---|---|---|
| Receptor binding | ||
| Artn | Artemin | 3.97 |
| Fgf5 | Fibroblast growth factor 5 | 2.73 |
| Cxcl2 | Chemokine (C-X-C motif) ligand 2 | 1.93 |
| Fgf14 | Fibroblast growth factor 14 | 1.91 |
| Bmp6 | Bone morphogenetic protein 6 | 1.82 |
| Npy | Neuropeptide Y | 1.69 |
| Tgfa | Transforming growth factor alpha | 1.68 |
| Frs3 | Fibroblast growth factor receptor substrate 3 | 1.55 |
| Edn1 | Endothelin 1 | 1.54 |
| Nts | Neurotensin | 1.53 |
| Cell surface receptor–linked signal transduction | ||
| Crhr2 | Corticotropin releasing hormone receptor 2 | 2.00 |
| Adcy7 | Adenylate cyclase 7 | 1.63 |
| Robo4 | Roundabout homolog 4 (Drosophila) | 1.58 |
| Cxcr4 | Chemokine (C-X-C MOTIF) receptor 4 | 1.56 |
| Ltbp1 | Latent transforming growth factor beta binding protein 1 | 1.55 |
| Adamts1 | A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 | 1.52 |
| Response to stimulus | ||
| Cryab | Crystallin, alpha B | 4.24 |
| Gpx3 | Glutathione peroxidase 3 | 2.86 |
| Hspb1 | Heat shock protein 1 (hsp25) | 1.68 |
| Hspa1a | Heat shock protein 1B (hsp70) | 1.62 |
| Cell adhesion | ||
| Dsc3 | Desmocollin 3 | 2.85 |
| Pcdh10 | Protocadherin 10 | 2.18 |
| Col2a1 | Procollagen, type II, alpha 1 | 1.74 |
| Col8a1 | Procollagen, type VIII, alpha 1 | 1.53 |
| Fn1 | Fibronectin 1 | 1.64 |
| Thbs2 | Thrombospondin 2 | 1.68 |
| Spp1 | Osteopontin | 1.52 |