Activation of GRE-mediated gene transcription by corticosteroids. a, Time-dependent effect of Dex (100 nM) on GRE promoter activity. b, Concentration-dependent effect of Dex on GRE promoter activity (fold induction) at 16 h. Values are means ± s.e.m.; n = 4; *, P < 0.05 compared with time 0 or untreated condition. c, Effects of Dex with and without RU, WM, ActD or DRB on pTAL-Luc (□) and pGRE-Luc (■) activities at 16 h. Values are means ± s.e.m.; n = 3; *, P < 0.05 compared with control (untreated).