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. Author manuscript; available in PMC: 2009 Apr 13.
Published in final edited form as: Nat Med. 2002 May;8(5):473–479. doi: 10.1038/nm0502-473

Fig. 5.

Fig. 5

NO-mediated cardioprotective effects of corticosteroids. a–d, TTC- and phthalo blue–stained, short-axis tissue sections of hearts removed from representative mice that were injected before coronary occlusion with PBS (control; a), Dex (b), Dex + RU486 (c), or Dex + L-NAME (d). White areas, infarcted tissue; blue areas, non-ischemic tissue; red areas, salvaged (viable) tissue within the risk region. Scale bar, 2 mm. e, Myocardial infarct size as a percentage of region at risk for infarction in C57Bl/6 mice treated with PBS (control), Dex, Dex + RU486, or Dex + L-NAME. Values are means ± s.e.m.; n = 8 per group; *, P < 0.05 compared with control. f, Corresponding NOS activities in hearts from mice treated similarly as in e as determined 90 min after the administration of Dex. Values are means ± s.e.m.; n = 5 per group; *, P < 0.05 compared with control.