Table 1.
Control (n = 8) |
Dex (n = 8) |
Dex + RU486 (n = 8) |
Dex + L-NAME (n = 8) |
|
---|---|---|---|---|
HR (pre) | 395 ± 9 | 346 ± 16* | 425 ± 13 | 374 ± 13 |
HR (dur) | 423 ± 12 | 403 ± 20 | 468 ± 17* | 401 ± 12 |
HR (post) | 436 ± 17 | 408 ± 9 | 468 ± 13 | 405 ± 9 |
Heart/BWT (%) | 0.48 ± 0.01 | 0.46 ± 0.01 | 0.51 ± 0.01 | 0.48 ± 0.02 |
LV/BWT (%) | 0.35 ± 0.01 | 0.32 ± 0.01* | 0.39 ± 0.018 | 0.36 ± 0.02 |
RR (% LV) | 35.6 ± 1.7 | 36.2 ± 3.3 | 40.5 ± 2.5 | 34.5 ± 2.9 |
IF/LV (%) | 19.2 ± 2.1 | 12.2 ± 2.4* | 20.7 ± 2.0 | 18.5 ± 2.8 |
Control, untreated; HR, heart rate before (pre), during (dur) and after (post) 30 min of ischemia; BWT, body weight; LV, left ventricle; RR, region at risk for ischemia; IF, infarct area. Values are means ± s.e.m.
P < 0.05 versus control group.