. Author manuscript; available in PMC: 2009 Apr 15.

Published in final edited form as: Cancer. 2009 Apr 15;115(8):1660–1668. doi: 10.1002/cncr.24184

TABLE 2. Risk of SCCHN Associated with the p73 Genotypes and Allele Frequencies in HPV16⁺ and HPV16^- Patients.

P73 Genotype	HPV16⁺ Patients (N = 85)		HPV16^- Patients (N = 117)		Crude OR (95% CI)	Adjusted OR (95% CI)^a

	No.	%	No.	%
G4C14-to-A4T14
GC/GC^b(^c)	33	38.8	65	55.5	1.00	1.00
GC/AT^b	42	49.4	49	41.9	1.69 (.94-3.04)	1.69 (.90-3.16)
AT/AT^b	10	11.8	3	2.6	6.57 (1.69-25.5)	5.32 (1.32-21.4)
Trend test					P = .003	P = .014
GC/AT+AT/AT	52	61.2	52	44.5	1.97 (1.12-4.48)	1.91 (1.03-3.53)
AT allele	.365		.235

Adjusted for age, sex, tobacco smoking and alcohol drinking status in a logistic regression model.

χ² = 9.937, P = .007 for genotype distributions; χ² = 8.047, P = .005 for allele frequency.

Reference group.

TABLE 2. Risk of SCCHN Associated with the p73 Genotypes and Allele Frequencies in HPV16+ and HPV16- Patients.