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. 2009 Apr 23;4(4):e5299. doi: 10.1371/journal.pone.0005299

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Woyke et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Genome streamlining was evidenced by small genome sizes, low fraction of genes in paralog families, and low fraction of non-coding bases. Included are all available genomes of the Bacteroidetes/Chlorobi group. The number of genes in paralog families was estimated using the BLASTCLUST tool from the NCBI BLAST software (>30% sequence similarity, across >50% of their length and E<10⁻⁶).