Table 1. Pharmacological manipulation of cytosolic calcium and calcium signaling.
na | drug 1 | effect 1 (nb) | drug 2 | effect 2 (nb) |
16 | ifenprodil 10 µM/10 min | no ER fission (16) | NMDA 100 µM | ER fission (16) |
20 | thapsigargin 0.2 µM/60 min | no ER fission (20) | - | - |
6 | thapsigargin 0.2 µM/10 min | no ER fission (6) | NMDA 100 µM | ER fission (6) |
10 | KN-93 10 µM/10 min | no ER fission (10) | NMDA 100 µM | ER fission (10) |
20 | staurosporine 20 µM/20 min | no ER fission (20) | NMDA 100 µM | ER fission (20) |
20 | DHPG 100 µM/60 min | no ER fission (20) | - | - |
Effect on ER structure.
Total number of neurons tested.
Number of neurons displaying the indicated response.