Table 2.
Cardiac surgical data in the overall population and homocysteine quintiles
| Factor | All patients | Homocysteine subgroups (quintiles)—range (μmol/L) |
P-value | ||||
|---|---|---|---|---|---|---|---|
| Median (IQR) or n (%) | I (1.7–9.8) | II (9.9–12.5) | III (12.6–14.8) | IV (14.9–19.1) | V (19.2–92.3) | ||
| Isolated coronary surgery | 262 (49.3) | 49 (46) | 51 (48) | 61 (57) | 44 (41) | 57 (52) | 0.637 |
| Isolated valve surgery | 156 (29.4) | 43 (41) | 29 (27) | 24 (22) | 32 (30) | 28 (26) | 0.317 |
| Combined procedure | 113 (21.3) | 16 (15) | 26 (24) | 21 (19) | 30 (28) | 20 (18) | 0.102 |
| CPB duration (min) | 68 (54–95) | 62 (52–84) | 68 (52–92) | 65 (51–101) | 75 (57–95) | 70 (55–96) | 0.048 |
| Closed, biocompatible circuits | 145 (27) | 28 (27) | 33 (31) | 28 (27) | 28 (27) | 28 (27) | 0.965 |
| Aortic cross-clamp time | 45 (35–66) | 42 (35–62) | 47 (36–64) | 42 (34–62) | 49 (37–69) | 46 (33–45) | 0.424 |
| Nadir haematocrit on CPB (%) | 27 (24–29) | 27 (24–29) | 28 (25–30) | 27 (24–29) | 28 (24–31) | 26 (24–29) | 0.966 |
| Nadir temperature on CPB (°C) | 32 (31.7–33) | 32 (32–33) | 32 (32–33) | 32 (32–33) | 32 (31–33) | 32 (32–33) | 0.747 |
CPB, cardiopulmonary bypass; IQR, interquartile range.