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. Author manuscript; available in PMC: 2009 Apr 24.
Published in final edited form as: Circ Res. 2008 Oct 2;103(9):965–973. doi: 10.1161/CIRCRESAHA.108.185793

Figure 7.

Figure 7

Preserved CD4+ T-cell priming in vivo under dyslipidemic conditions. LDLR−/− animals on a 2.5-month diet were immunized with ovalbumin/CFA, and polyclonal CD4+ T cells were isolated from draining lymph nodes and restimulated ex vivo with DCs from wild-type donors. Regardless of the dose of antigen presented (ovalbumin 10 or 100 µg/mL), effector CD4+ T-cell proliferation in response to a second ex vivo antigenic stimulation was unaltered, whether priming occurred in vivo under atherosclerotic (HF) or control conditions. *P<0.01, †P<0.05.