Table A2.

Baseline Characteristics and Presence of Low GFR Main Cohort (Age 35–84)

	Age- & sex-adjusted model*		Multivariable model		Most parsimonious model
Characteristic	Odds Ratio (95% CI)	p-value	Odds Ratio (95% CI)	p-value	Odds Ratio (95% CI)	p-value
Sex (Ref: Men)	1.46 (1.13,1.89)	0.004	1.46 (1.03,2.06)	0.03	1.46 (1.03,2.06)	0.03
Education (Ref: < HS)	0.92 (0.72,1.17)	0.5	N/A
Income (Ref: Low)	0.85 (0.65,1.11)	0.2	N/A
Marital Status (Ref: Married)	1.32 (1.03,1.69)	0.03	1.37 (1.01,1.86)	0.04	1.37 (1.01,1.86)	0.04
Insured (Ref: No)	1.26 (0.79,2.01)	0.3	N/A
Hypertension (Ref: No)	5.51 (3.38,8.97)	< 0.001	3.12 (1.82,5.33)	<0.001	3.12 (1.82,5.33)	<0.001
Type 2 Diabetes (Ref: No)	2.73 (2.14,3.48)	< 0.001	1.43 (1.04,1.98)	0.03	1.43 (1.04,1.98)	0.03
CVD (Ref: No)	3.29 (2.52,4.31)	< 0.001	2.54 (1.82,3.54)	<0.001	2.54 (1.82,3.54)	<0.001
Hypercholesterolemia (Ref: No)	1.79 (1.39,2.32)	< 0.001	1.46 (1.09,1.96)	0.01	1.46 (1.09,1.96)	0.01
Low HDL (Ref: No)	1.47 (1.12,1.91)	0.005	1.1 (0.81,1.49)	0.6	1.1 (0.81,1.49)	0.6
Hypertriglyceridemia (Ref: No)	2.23 (1.67,2.99)	< 0.001	1.68 (1.20,2.36)	0.003	1.68 (1.20,2.36)	0.003
Waist (per 5 cm)	1.08 (1.04,1.12)	< 0.001	1.03 (0.98,1.08)	0.3	1.03 (0.98, 1.08)	0.3
Physical Activity (per SD)	0.70 (0.59,0.81)	< 0.001	0.81 (0.70,0.95)	0.01	0.81 (0.70,0.95)	0.01
Age (per 5 years)	1.56 (1.47,1.65)	< 0.001	1.42 (1.31,1.55)	<0.001	1.42 (1.31,1.55)	<0.001

Abbreviations: HS, high school; GFR, glomerular filtration rate; CVD, cardiovascular disease; HDL, high-density lipoprotein; N/A, ***.