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Cytokinesis failure in the absence of human augmin. (A) Binucleated cells were increased after hDgt6 RNAi. (B) Cleavage furrow regression was observed after hDgt6 RNAi (40–45 min) (phase-contrast image). Images were acquired every 5 min. (C) Lowered central spindle MT density (green) after hDgt6 RNAi in late anaphase. Blue, DNA. (D) Localization of GFP-hDgt6 and γ-tubulin on the central spindle MTs during late anaphase. (Scale bars, 5 μm.)
