. Author manuscript; available in PMC: 2010 Mar 30.

Published in final edited form as: Virology. 2009 Jan 31;386(1):94–101. doi: 10.1016/j.virol.2008.12.040

Table 1.

Vertical transmission of SV40 from maternal hamsters inoculated during pregnancy to progeny animals^a

Days after birth	Viral strain (No. positive litters)^b	No. progeny tested	Tissue	No. tissues positive/No. tested (%)^c	Viral loads (copies/10⁶ cells) Range (mean)^d
1, 3	Baylor-2E (2)	30	Kidney Lung	1/29 (3) 3/30 (10)	649 (649) 234-1,944 (1,192)
7	Baylor-1E (1) SVCPC (2)	23	Spleen Kidney Lung Brain	4/21 (19) 1/20 (5) 4/19 (21) 0/17 (0)	817-2,406 (1,452) 23,966 (23,966) 488-2,532 (1,623) <5 (<5)
14	SVCPC (1) SVPML-1 (1)	22	Spleen Kidney Lung Brain	1/22 (5) 0/22 (0) 0/20 (0) 4/22 (18)	1,020 (1,020) <5 (<5) <5 (<5) 477-908 (719)
21	SVPML-1 (1)	12	Spleen Kidney Lung Brain	0/12 (0) 1/10 (10) 0/12 (0) 2/12 (17)	<5 (<5) 376 (376) <5 (<5) 477-893 (685)

Pregnant hamsters were inoculated intraperitoneally with 10⁷ PFU of SV40.

Vertical transmission was not detected in litters from 6 additional animals inoculated with SV40 strains Baylor-1E, Baylor-2E, SVCPC, and SVPML-1 and harvested at 3, 7/14/21, 21, and 7 days after birth, respectively (data not shown).

One tissue slice per organ was analyzed for SV40 DNA.

Viral loads among virus-positive samples.