Table 4.
Evidence of SV40 vertical transmission and persistence of virus in progeny animals 6 months after birth
| Strain/variant (regulatory region) | No of litters positive/No. tested (%) | No. progeny positive/No. tested (%) | Tissue | No. tissues positive/No. tested (%) | Viral load (copies/106 cells) Range (mean)a |
|---|---|---|---|---|---|
| SVCPC (simple) |
1/1 (100) | 1/5 (20) | Spleen Kidney Lung |
1/1 (100) 0/5 (0) 0/5 (0) |
2,343 (2,343) <5 <5 |
| 776-2E (complex) |
1/2 (50) | 5/9 (56) | Spleen Kidney Lung |
1/7 (14) 0/9 (0) 5/9 (56) |
615 (615) <5 518-3,539 (1,800) |
| Total: | 2/3 (67) | 6/14 (43) | 7/36 (19) | 518-3,539 (1,721) | |
a
Viral loads among virus-positive samples.