A, Hematoxylin & eosin staining, B, immunodetection of αA-crystallin and C, αB-crystallin, and D, TUNEL (red)/DAPI nuclear staining (blue) in human retinocytoma.
A, Retinocytoma cells represent a relatively uniform nuclear shape with no apparent nuclear atypia. Mitotic figures are not observed in the tumor tissue. B, αA-crystallin is strongly expressed in the cytoplasm of all tumor cells. C, αB-crystallin immunoreactivity is weakly detected in tumor cells. D, Apoptotic cell is rarely detected in retinocytoma tissue (arrow).
Bar indicates 50μm.