Table 2.
Randomized controlled trials of the effects of disease management on depression
| Disease | Authors | # Subjects | Time | Treatment | Control Condition | Outcome Measure for Depression |
|---|---|---|---|---|---|---|
| Coronary Heart Disease | Horlick et al., (1984) | 116 | 6 week intervention 24 week follow-up | Education/Group Discussion | Usual Care | = MMPI |
| Congestive Heart Failure | Rogers et al., 1994 | 5,025 | 2 years | Enalapril | Placebo | = POMS |
| Hypertension | Perez-Stable et al., (2000) | 312 | 52 weeks | Propanolol | Placebo | = CESD, BDI |
| Diabetes | ||||||
| Piette et al., (2000) | 240 | 52 weeks | ATDM | Usual Care | + CESD | |
| Wing et al., (1986) | 50 | 12 week intervention follow-up at 48 weeks | Behavioral Weight Control + Glucose Self- | Standard Behavioral Weight Control | + BDI | |
| Arthritis | ||||||
| Lorig et al., (1999) | 331 | 6 week intervention 4 month followup | ASMP | Wait List | = CESD | |
| Barlow et al., (2000) | 240 | 6-weeks | ASMP | Wait List | +HADS | |
| 4 month follow up | ||||||
| Cancer | McQuellon et al., (1998) | 180 | 1 day | Orientation Intervention | Usual Care | + POMS, CESD |
“+” = Depression treatment improved outcome; “=” = no difference
HRSD = Hamilton Rating Scale for Depression; BDI = Beck Depression Inventory; POMS = Profile of Mood States; MMPI = Minnesota Multiphasic Personality Inventory; CESD = Center for Epidemiologic Depression Scale; HADS = Hospital Anxiety and Depression Scale; ASMP = Arthritis Self-Management Program; ATDM = Automated telephone disease management.