Table 2.
Gene Ontology enrichment by biological process and cellular localization of genes identified by functional profiling
| BIOLOGICAL PROCESS | CELLULAR COMPONENT | ||||
| Category | p-value1 | # genes2 | Category | p-value1 | # genes2 |
| Transport | 1.87 E-14 | 53 | Endosome | 5.24 E-10 | 11 |
| Organelle organization and biogenesis | 2.44 E-12 | 41 | Peroxisome | 5.11 E-07 | 9 |
| Peroxisome organization and biogenesis | 6.98 E-12 | 11 | Cytoplasm | 3.94 E-06 | 73 |
| Intracellular protein transport | 3.11 E-11 | 32 | Peroxisomal membrane | 6.98 E-06 | 5 |
| Protein transport | 6.79 E-10 | 33 | Intracellular | 1.16 E-04 | 98 |
| Protein-peroxisome targeting | 4.41 E-09 | 7 | Cell | 1.75 E-04 | 102 |
| Protein targeting | 4.99 E-09 | 22 | AP-3 adaptor complex | 3.76 E-03 | 2 |
| Cytoplasm organization and biogenesis | 1.82 E-08 | 41 | Vacuolar membrane | 6.58 E-03 | 5 |
| Vacuole organization and biogenesis | 6.98 E-07 | 14 | Hydrogen-translocating V-type ATPase complex | 7.16 E-03 | 3 |
| Protein-vacuolar targeting | 1.90 E-06 | 10 | Membrane | 7.28 E-03 | 28 |
1Calculated from hypergeometric distribution P < 0.01
2Number of identified genes in the Gene Ontology (GO) category
Enriched categories were identified using Funspec; see Additional file 4 for complete tables.