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. 2009 Apr 24;4(4):e5323. doi: 10.1371/journal.pone.0005323

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Wray et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Cells stably transfected with vector control, or Metnase shRNA were treated with VP-16 (A) or adriamycin (B) and colony survival was measured as described. Values are averages ±SEM for three determinations. (C) Cells transfected with control (shGFP) or Metnase shRNA were treated with 1 µM adriamycin for 24 hrs and apoptosis (annexin-V) and cell death (propidium iodide) were analyzed by FACS. Values are averages (+SEM) for three determinations.