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. 2009 Apr 24;4(4):e5323. doi: 10.1371/journal.pone.0005323

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Wray et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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kDNA was incubated with varying amounts of Topo IIα (lanes 1–4), Topo IIα and adriamycin (lane 5), Metnase alone (lane 6), Metnase and adriamycin (lane 7), or Topo IIα and Metnase (lane 8). In lanes 9 and 10, kDNA was incubated with Topo IIα, Metnase and adriamycin with different orders of addition as indicated below.