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. 2008 Nov;125(3):359–369. doi: 10.1111/j.1365-2567.2008.02858.x

Figure 7.

Figure 7

Collagen IV (Coll IV) enhances interleukin (IL)-7-induced cell survival. Effector CD4+ T cells were stimulated or not in the absence of IL-2 with IL-7, Coll IV or IL-7 + Coll IV. As a control, the cells were also cultured in the presence of IL-2. After 72 hr, cell apoptosis was determined by Annexin V/7AAD staining and fluorescence-activated cell sorting (FACS) analysis. The results are presented as mean values from three independent experiments performed in triplicate with T cells from different blood donors, with standard errors as indicated. Statistical analysis was carried out using Student’s t-test: *P < 0·05 between IL-7-treated and untreated (med) samples. **P < 0·05 between IL-7 + Coll IV- and IL-7-treated samples.