Table 3.
A to I editing observed in PDE8A1 gene transcripts of normal and IFN activated T lymphocytes
| Edited base number | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Sample | Clones | 42423 | 42424 | 42454 | 42456 | 42457 | 42466 | 42535 | others |
| Control 1 | 40 | 2 | 18 | 4 | 2 | 7 | 1 | 3 | 2 |
| Control 2 | 40 | 1 | 22 | 2 | 3 | 4 | 3 | 2 | 1 |
| Control 3 | 40 | 2 | 19 | 4 | 1 | 4 | 3 | 3 | 1 |
| Total | 120 | 5 (4·17) | 59 (49·17) | 10 (8·33) | 6 (5·00) | 15 (12·50) | 7 (5·83) | 8 (6·67) | 4 (3·33) |
| IFN-activated cells 1 | 40 | 0 | 17 | 2 | 0 | 0 | 0 | 0 | 3 |
| IFN-activated cells 2 | 40 | 0 | 15 | 0 | 0 | 0 | 0 | 0 | 2 |
| IFN-activated cells 3 | 40 | 0 | 12 | 0 | 0 | 0 | 0 | 0 | 2 |
| Total | 120 | 0 | 44 (36·67)* | 2 (1·67)* | 0 | 0 | 0 | 0 | 7 (5·83) |
Percentage of editing at each site is indicated in parentheses; Others, edited base number 42256, 42259, 42322, 42341, 42346, 42366; Statistical significance
P-value < 0·05.