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. 2009 Apr 24;4(4):e5290. doi: 10.1371/journal.pone.0005290

Table 1. Average full-field ERG values at various timepoints.

Nanoparticle Naked DNA Changeb Pb
Averagea±SEM #c Averagea±SEM #c
PI-30
Scotopic-A CBA-NMP 134.8±13.3 19 92.9±9.4 6 41.9 µV, 45.1% 0.018
IRBP-NMP 146.7±13.7 15 96.0±11.0 9 50.7 µV, 52.8% 0.018
Photopic-B CBA-NMP 148.1±11.3 19 98.7±15.2 6 49.4 µV, 50.1% 0.035
IRBP-NMP 134.4±13.7 15 92.4±9.7 9 42.0 µV, 45.4% 0.040
PI-60
Scotopic-A CBA-NMP 107.7±7.8 5 81.8±17.2 4 25.9 µV, 31.7% 0.061
IRBP-NMP 148.4±8.9 10 70.5±18.8 4 77.9 µV, 110.4% 0.011
Photopic-B CBA-NMP 117.3±19.7 5 131.0±11.3 4 −13.7 µV, −11.5% 0.594
IRBP-NMP 194.8±16.0 10 64.5±20.4 4 130.3 µV, 202.0% 0.0007
PI-120
Scotopic-A CBA-NMP 123.9±12.9 5 77.1±17.3 6 46.8 µV, 60.7% 0.086
IRBP-NMP 129.4±9.6 5 67.6±16.2 5 61.8 µV, 91.4% 0.011
Photopic-B CBA-NMP 120.8±14.83 5 108.0±13.48 6 12.8 µV, 11.8% 0.54
IRBP-NMP 185.6±20.6 5 87.9±20.5 5 97.7 µV, 111.1% 0.009
a

Values are mean µV±S.E.M.

b

Comparison between nanoparticle and naked DNA using 2-tailed un-paired Student's t-test as described in methods.

c

Number of animals tested.