TABLE 4.

Effects of C. albicans RFX2 on the expression of hypha-specific genes

Gene	Relative mRNA transcript levela in indicated strain
	In YPD at 30°C				After UV radiation
	SC5314	rfx2 heterozygous mutant	rfx2 null mutant	RFX2 reinsertion strain	SC5314	rfx2 heterozygous mutant	rfx2 null mutant	RFX2 reinsertion strain
HWP1	1.02 ± 0.02	4.41 ± 0.2*	14.43 ± 0.59*	5.10 ± 2.32*	14.55 ± 0.35*	13.96 ± 2.50*	33.30 ± 6.95*	15.90 ± 2.75*
ECE1	0.96 ± 0.04	4.69 ± 1.53*	16.82 ± 0.51*	4.99 ± 2.50*	4.86 ± 0.05*	4.97 ± 3.16*	29.26 ± 3.04*	16.24 ± 2.56*
ALS3	1.00 ± 0.02	1.52 ± 0.01	5.18 ± 0.06*	1.44 ± 0.01	2.31 ± 0.02*	4.81 ± 0.07*	8.70 ± 0.17*	5.51 ± 0.21*
HYR1	1.01 ± 0.02	7.33 ± 2.15*	13.34 ± 0.16*	8.42 ± 0.40*	11.04 ± 0.09*	7.42 ± 0.36*	14.28 ± 1.00*	9.25 ± 1.43*
CEK1	1.00 ± 0.01	1.53 ± 0.97	4.21 ± 0.08*	1.82 ± 0.30	1.84 ± 0.01	1.74 ± 0.02	3.32 ± 0.71*	2.46 ± 0.32*

^aAsterisks denote biological (increase of more than twofold) and statistical (P < 0.05) significance of the level of expression by the respective strains compared with the level of expression by SC5314.