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. Author manuscript; available in PMC: 2009 Aug 1.
Published in final edited form as: Dev Biol. 2008 Jun 13;321(1):101–110. doi: 10.1016/j.ydbio.2008.06.004

Figure 1.

Figure 1

Molecular analysis of zebrafish barx1. (A) The coding region of barx1 consists of four exons (boxes, numbered with Roman numerals) containing the homeobox (HB, blue) and the Bar Basic Region (BBR, green); UTR’s are indicated by outlined boxes. Target sites of the barx1 ATG morpholino (Bx MO) and the Splice acceptor site morpholino (Sa MO) are indicated. (B) Phylogenetic tree comparing zebrafish (z) Barx1 with the human (h), mouse (m), and chicken (c) Barx amino acid sequences, as examined using Clustal W. GenBank Accession Nos.: (h1) NM021570, (m1) NM007526, (c1) NM204193, (z1) NM001024949, (h2) NM003658, (m2) NM013800, (c2) NM204896, (z2) XM001342008 respectively. (C) Syntenic relationship between zebrafish chromosome 11 fragment contig: CR548622.8 (Ensembl release 49, March 2008) and the human chromosome 9q22.32 (loci distances indicated in Mb). The barx1 and phf2, PHD finger protein 2, are linked in zebrafish and humans.