Figure 5. IKKβ deficiency results in increased astrogliosis in brains of hypoxic mice.
Mice of the indicated genotypes were kept under normoxia or hypoxia (O2 = 8%) for 24 hrs. After this period the mice were perfused with a fixative and the brain was collected and frozen. Brain sections at the cerebellar region (10 μm) were stained with an antibody against GFAP (an astrocyte marker). Magnification x20.