Table 2.

Comparison of in vivo left ventricular functional parameters in lean control untreated ZDF, ZDF + trientine, and ZDF + citric acid at 32 weeks of age. Values are presented as mean ± SEM. n = 4–6 per group. ∗ denotes P < .05 versus age-matched lean control. † denotes P < .05 versus untreated ZDF.

	Heart rate (bpm)	Cardiac output (mL/min)	Stroke volume (μL)	End diastolic pressure (mmHg)	End systolic pressure (mmHg)	Max dP/dt	Min dP/dt
Lean control	291 ± 9	38 ± 2	121 ± 5	7 ± 0.4	132 ± 7	7244 ± 332	−7533 ± 554
ZDF	279 ± 7	39 ± 3	150 ± 9*	10 ± 0.6*	135 ± 7	7423 ± 500	−6777 ± 518
ZDF + trientine	270 ± 12	35 ± 4	130 ± 9	7 ± 0.3†	136 ± 11	7184 ± 576	−7392 ± 376
ZDF + citric acid	248 ± 13*	31 ± 2	122 ± 5	7 ± 0.5†	129 ± 13	6509 ± 484	−6659 ± 707