Table 2.
Age- and Sex-Adjusted Distribution of Demographic and Health-Related Characteristics by Brain MR Imaging Patterna
| Characteristic | No Lesions | Focal Lesions | Diffuse WMLs |
|---|---|---|---|
| Follow-up time to HF or censoring, y | 274±6.5 | 140±6.3 | 406±6.4 |
| Age, y | 70.7±5.5 | 72.6±6.5b | 75.5±6.9c,d |
| Age <80 y | 92 | 84 | 71c,d |
| Male sex | 45 | 46 | 38c,d |
| Education, y | 4.6 ±2.1 | 4.6±2.5 | 4.3± 2.1c |
| Body mass indexe | 27.9±4.1 | 27.4±4.3 | 26.9±4.3 |
| Smoking status | |||
| Never | 62 | 55 | 60d |
| Former | 31 | 35 | 29 |
| Current | 7 | 10 | 11 |
| Physical activity | |||
| Sedentary | 8 | 11 | 15c |
| Intermediate | 61 | 67 | 61 |
| Active | 31 | 23 | 25 |
| Blood pressure, mm Hg | |||
| Systolic | 144.7 ± 18.6 | 146.9 ± 19.9 | 150.5 ± 19.9c |
| Diastolic | 78.8 ± 11.2 | 78.7 ± 11.9 | 79.2 ± 11.8 |
| Orthostatic hypotension | 18 | 15 | 18 |
| Ever fell during past year | 28 | 24 | 30 |
| No. of falls during past year | 0.5±1.0 | 0.44±0.95d | 0.7±1.7c,d |
| Disease status | |||
| Previous HF | 2.5 | 2.8 | 2.7 |
| Other fractures after age 50 y | 29 | 33 | 28 |
| Stroke | 1 | 6b | 4c |
| Osteoporosis | 46 | 45 | 50c |
| Diabetes mellitus | 9 | 7 | 8 |
| Any urinary incontinence | 17 | 25 | 24c |
| Physical and cognitive function | |||
| Activities of daily living disability | 6 | 12 | 18c,d |
| Short physical performance battery score | 9.4±2.3 | 9.0±2.6d | 8.1±2.8c,d |
| Mini-Mental State Examination score | 25.8±3.3 | 24.8±3.9b | 23.6±4.6c |
| No. of medications | 2.8±2.3 | 3.1±2.6 | 3.5±2.5c,d |
| Taking high blood pressure medication | 29 | 39b | 28d |
Abbreviations: HF, hip fracture; MR, magnetic resonance; WMLs, white matter lesions.
Data are given as mean±SD or as percentages unless otherwise indicated. Percentages may not total 100% owing to rounding.
P<.05 comparing focal lesions with no lesions.
P<.05 comparing diffuse WMLs with no lesions.
P<.05 comparing diffuse WMLs with focal lesions. From linear regression models for continuous variables, from logistic regression models for dichotomous variables, and from polynomial logistic regression models for multilevel variables.
Calculated as weight in kilograms divided by height in meters squared.