Table 3. Hip Fracture (HF) Incidence Rates per 1000 Person-Years and Age-Adjusted Relative Risks (RRs) of HF by Brain Magnetic Resonance (MR) Imaging Pattern, Age Group, and Sexa.
| Overall | Age <80 y | Age ≥80 y | Men | Women | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variable | Rate per 1000 Person-Years | Age-Adjusted RR (95% CI) | Rate per 1000 Person-Years | Age-Adjusted RR (95% CI) | Rate per 1000 Person-Years | Age-Adjusted RR (95% CI) | Rate per 1000 Person-Year | Age-Adjusted RR (95% CI) | Rate per 1000 Person-Years | Age-Adjusted RR (95% CI) |
| With MR Imaging | ||||||||||
| (n=820; 51 HF) | (n=659; 31 HF)b | (n=161; 20 HF)c | (n=343; 11 HF) | (n=477; 40 HF) | ||||||
| Brain MR | ||||||||||
| Imaging pattern | ||||||||||
| Diffuse WMLs | 14.8 | 1.8 (0.9-3.8) | 10.3 | 2.7 (1.1-7.0) | 28.7 | 1.1 (0.3-3.5) | 8.6 | 1.7 (0.3-8.5) | 19.5 | 1.7 (0.7-4.1) |
| Focal lesions | 6.1 | 1.1 (0.3-3.1) | 5.6 | 1.9 (0.5-6.9) | 8.8 | 0.3 (.03-3.0) | 5.7 | 2.1 (0.3-15.3) | 2.1 | 0.5 (0.1-2.7) |
| No lesions | 7.1 | 1.0 [Reference] | 5.7 | 1.0 [Reference] | 24.5 | 1.0 [Reference] | 2.9 | 1.0 [Reference] | 10.0 | 1.0 [Reference] |
| Total rate | 10.6 | … | 7.7 | … | 25.0 | … | 5.9 | … | 13.5 | … |
| Refused MR Imaging | ||||||||||
| (n=77 7; 46 HF) | (n=39 0; 18 HF) | (n=388; 28 HF) | (n=2 75; 10 HF) | (n=503 ; 36 HF) | ||||||
| Total rate | 11.6 | … | 7.9 | … | 16.5 | … | 7.7 | … | 13.5 | … |
Abbreviations: CI, confidence interval; WMLs, white matter lesions; ellipses, not applicable.
a
Age-adjusted RRs were calculated from Cox proportional hazards regression models, adjusted for age as a continuous variable.
b
Of these 31 HFs, 9, 2, and 20 HFs were recorded among those with diffuse WMLs, focal lesions, and no lesions, respectively.
c
Of these 20 HFs, 3, 1, and 16 HFs were recorded among those with diffuse WMLs, focal lesions, and no lesions, respectively.