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Types of PTEN mutations and alterations of amino acids in XP melanomas
| XP Melanoma (number of PTEN mutations) | % | AA changed* (number) | |
|---|---|---|---|
| Transitions | |||
| G:C to A:T | 23 | 42.5 | 15 |
| A:T to G:C | 23 | 42.5 | 15 |
| Transversions | |||
| G:C to T:A | 3 | 5.5 | 3 |
| G:C to C:G | 1 | 2 | 1 |
| A:T to T:A | 3 | 5.5 | 2 |
| A:T to C:G | 1 | 2 | 1 |
| Total | 54 | 100 | 37 (69%) |
*including 33 missense, 2 nonsense and 2 splicing mutations (from Table 2)
