Fig. 1.
Effect of AAT deficiency on cytokine production in stimulated whole blood. Cytokine production was measured in undiluted, S. epi-stimulated blood obtained from nine AAT-deficient patients (•) and from 10 healthy controls (▪). After 18 h of stimulation, supernatants were removed for cytokine assays, including IL-8 (A), IL-6 (B), TNF-α (C), IL-1β (D), IL-1Ra (E), and IL-10 (F). Horizontal bars indicate median levels. **, P < 0.005, and ***, P < 0.0005, compared with healthy controls.
