Figure 2.

Efficacy and reproducibility of SSTA. A) Human keratinocyte cDNA control (left panel) or mouse liver cDNA diluted 1:10 with human keratinocyte cDNA (right panel) were treated with SSTA using a mouse reference, labeled with Cy5 dye (red) and hybridized to microarrays along with a Cy3 common reference (green). B) Scatter plots of replicates of mouse liver (mL) cDNA diluted 1:10 with human keratinocyte (hK) cDNA either SSTA-treated (SSTA+) or untreated (SSTA−). C) Hierarchical clustering of mouse liver or mouse muscle (mM) cDNA diluted 1:10 with human cDNA or left undiluted. Replicates were hybridized to arrays with or without prior SSTA treatment. Hierarchical clustering of samples was performed using average linkage clustering.