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Effect of stromal fibroblasts on tumor development from organoids transduced with Her2/SV40er
| Experimental set | Organoids | Fibroblasts | Total sites | Tumor frequency, no. (%) |
|---|---|---|---|---|
| A | Donor 1 | RMF-HGF | 10 | 10 of 10 (100) |
| B | Donor 1 | RMF-HGF | 4 | 4 of 4 (100) |
| C | Donor 2 | RMF-HGF | 6 | 6 of 6 (100) |
| D | Donor 3 | RMF-HGF | 6 | 5 of 6 (83) |
| E | Donor 4 | RMF-HGF | 6 | 5 of 6 (83) |
| F | Donor 5 | RMF-HGF | 6 | 6 of 6 (100) |
| G | Donor 1 | RMF | 4 | 3 of 4 (75) |
| H | Donor 1 | 1°RMF-1 | 6 | 0 |
| I | Donor 1 | 1°RMF-2 | 6 | 1 of 6 (17) |
| J | Donor 1 | None | 9 | 1 of 9 (11) |
