Figure 1.

Unsupervised hierarchical clustering of miRNAs. The expression levels of miRNAs were presented as normalized cy5/cy3 ratios, upregulated miRNAs were shown as red and downregulated miRNAs were shown as green. I6, H9 and BG01v are names of human embryonic stem (hES) cells lines. P denoted the number of passages of the cell lines. H9-EB denoted embryoid body (EB) prepared from cell line H9 and the day indicates the time in culture. HMVEC = human microvascular endothelial cells, HUVEC = human umbilical vein endothelial cells, UASMC = umbilical artery smooth muscle cells; NHA = normal astrocyte and LFB = lung fibroblasts. Unsupervised hierarchical clustering analysis separated the samples to three major groups: hES cells, embryoid body (EB), and adult cells.