Table 5.

Annual average drug costs per patient for different antihypertensives according to the pattern of persistence [23]

Antihypertensive	Continuers [95%CI]	Switchers [95%CI]	Discontinuers 95%CI]	Total [95%CI]
Diuretics	€ 65.09 [58.67–71.52]	€ 153.10 [137.59–168.62]	€ 8.17 [7.60–8.75]	€ 33.45 [30.97–35.93]
Beta-blockers	€ 109.29 [102.46–116.12]	€ 158.73 [139.61–177.84]	€ 22.52 [24.24-23.79]	€ 63.40 [59.94–66.86]
Calcium-channel blockers	€ 234.63 [224.78–244.47]	€ 199.62 [183.45–215.78]	€ 38.24 [36.78–39.70]	€ 104.43 [100.07–108.79]
ACE inhibitors	€ 196.28 [189.69–202.86]	€ 237.53 [222.28–252.79]	€ 34.76 [33.53–35.99]	€ 108.25 [104.43–112.09]
Angiotensin II antagonists	€ 326.16 [313.05–339.27]	€ 268.07 [241.55–294.39]	€ 67.10 [62.89–71.31]	€ 201.53 [191.24–211.81]
Total	€ 171.73 [167.43–176.04]	€ 205.10 [196.85–213.34]	€ 28.29 [27.62–28.97]	€ 88.09 [86.10–90.08]

CI, confidence interval