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. Author manuscript; available in PMC: 2010 Mar 27.
Published in final edited form as: J Mol Biol. 2009 Mar 27;387(2):284–294. doi: 10.1016/j.jmb.2009.01.064

Figure 2.

Figure 2

Ca2+-independent binding of a) syt1C2A, b) syt1C2B and c) syt1C2AB fragments of synaptotagmin 1 to membranes composed of POPC:POPS (3:1), using a vesicle sedimentation assay (see Methods). The lines are fits to Eq. 2 and the values of K are given in Table 1. No binding of syt1C2A to POPC:POPS is detected in the absence of Ca2+.