Table 3.

Association of CD4⁺ forkhead box P3 (FoxP3)⁺/CD4⁺ proportion, FoxP3⁺/CD8⁺ and FoxP3⁺/CD25⁺FoxP3⁻ ratios with patient and tumour variables.

	CD4+FoxP3+/CD4+		FoxP3+/CD8+		FoxP3+/CD25+FoxP3−
Characteristic	MR	P-value	MR	P-value	MR	P-value
Gender*
Male	27·89	0·275	29·88	0·560	30·04	0·968
Female	34·20		33·27		29·80
Age (years)*
< 50	28·42	0·821	27·16	0·211	30·88	0·746
≥ 50	29·42		32·89		29·40
Race*
Chinese	25·07	0·079	26·55	0·090	29·48	0·820
Non-Chinese	32·79		34·19		30·50
Histological type†
SCC (type I)	45·79	0·001	48·14	0·002	45·57	0·001
NKC (type II)	29·96		28·17		23·04
UC (type III)	23·38		28·07		32·62

^*Mann–Whitney U-test;

^†Kruskal–Wallis test.

MR, mean rank. SCC (type I), squamous cell carcinoma; NKC (type II), non-keratinizing carcinoma; UC (type III), undifferentiated carcinoma.