Table 3.
The effect of age and cytomegalovirus (CMV) on CD4+ T cell number µl/blood.
| Age | CMV status | n = M/F | CD4 cells (±s.d.) | CD4 naive (±s.d.) | CD4 central memory (±s.d.) | CD4 effector memory (±s.d.) | CD4 memory cells (±s.d.) | T regulatory cells (±s.d.) |
|---|---|---|---|---|---|---|---|---|
| 20–40 | CMV+ | 5 (3/2) | 849·6 ± 84·0 | 139·8 ± 18·8 | 351·6 ± 33·6 | 358·2 ± 80·0 | 709·8 ± 79·6 | 46·13 ± 4·0 |
| CMV− | 15 (10/5) | 911·6 ± 69·9 | 338·3 ± 52·4 | 357·6 ± 30·5 | 215·7 ± 25·9 | 573·2 ± 42·8 | 42·87 ± 5·4 | |
| 40–60 | CMV+ | 12 (4/8) | 861·5 ± 69·5 | 261·2 ± 47·4 | 315·5 ± 34·6 | 284·8 ± 29·4 | 600·2 ± 56·1 | 42·91 ± 6·7 |
| CMV− | 9 (6/3) | 660 ± 62·3 | 172·0 ± 34·3 | 295·5 ± 51·3 | 192·5 ± 34·6 | 488 ± 58·1 | 52·01 ± 9·6 | |
| 60+ | CMV+ | 32 (8/24) | 714·5 ± 47·8 | 210·5 ± 28·2 | 261·1 ± 22·3 | 242·9 ± 29·5 | 504 ± 36·9 | 51 ± 5·1 |
| CMV− | 26 (8/18) | 737·8 ± 80·7 | 231·8 ± 36·4 | 342·3 ± 45·4 | 161·7 ± 25·3 | 504 ± 54·1 | 62·90 ± 12·3 |
A significant association was found with respect to CMV and effector memory cells (P = 0·0016). No significant associations were found because of age, gender and CMV on absolute CD4 counts, total memory, central memory or naive CD4 T cell counts. Age, CMV and gender did not have a significant effect on the T regulatory CD4 cell numbers. M/F, male/female; s.d., standard deviation.