Table 4.

Summary Of Overall MCG Data For The Detection Of Relevant Coronary Stenosis. n = number of cases; TP = true positives; TN = true negatives; FP = false positives; FN = false negatives; a priori = a priori probability of stenosis; Correct = fraction of correctly predicted cases; Sens = sensitivity; Spec = specificity; PPV = positive predictive value; NPV = negative predictive value; LR+ = positive likelihood ratio; LR- = negative likelihood ratio; OR = odds ratio; ROC AUC = receiver operating curve area under the curve for continuous severity score; 95% CI = 95% confidence interval; Lower = Lower boundary of 95% CI; Upper = Upper boundary of 95% CI; NaN = not a number; Revasc = coronary revascularization in medical history.

												ROC AUC							Odds Ratio
	n	TP	TN	FP	FN	Sens.	Spec.	PPV	NPV	Correct	a piori	ROC AUC	lower CI	upper CI	PPV (Bayes)	NPV (Bayes)	LR+	LR-	Odds Ratio	lower CI	upper CI
Combined Analysis
Total	1076	426	515	94	41	0.912	0.846	0.819	0.926	0.875	0.434	0.881	0.860	0.903	0.777	0.942	5.910	0.104	56.925	38.594	83.963
USA	136	72	45	17	2	0.973	0.726	0.809	0.957	0.860	0.544	0.886	0.825	0.946	0.835	0.950	3.548	0.037	95.294	21.014	432.131
Asia	189	73	97	15	4	0.948	0.866	0.784	0.971	0.899	0.407	0.914	0.868	0.961	0.770	0.972	7.079	0.060	118.017	37.594	370.482
Germany	751	281	373	62	35	0.889	0.857	0.819	0.914	0.871	0.421	0.873	0.846	0.900	0.767	0.936	6.239	0.129	48.301	31.034	75.175
female	390	121	221	38	10	0.924	0.853	0.761	0.957	0.877	0.336	0.885	0.849	0.920	0.617	0.978	6.296	0.089	70.371	33.878	146.172
male	686	305	294	56	31	0.908	0.840	0.845	0.905	0.873	0.490	0.881	0.853	0.908	0.839	0.908	5.673	0.110	51.653	32.377	82.405
< 65 years	623	216	332	47	28	0.885	0.876	0.821	0.922	0.880	0.392	0.892	0.865	0.920	0.747	0.948	7.138	0.131	54.492	33.108	89.688
65+ years	453	210	183	47	13	0.942	0.796	0.817	0.934	0.868	0.492	0.858	0.821	0.896	0.812	0.936	4.608	0.073	62.897	32.987	119.926
Female, < 65 years	184	43	121	12	8	0.843	0.910	0.782	0.938	0.891	0.277	0.896	0.838	0.953	0.579	0.975	9.345	0.172	54.198	20.754	141.533
Female, 65+ years	206	78	100	26	2	0.975	0.794	0.750	0.980	0.864	0.388	0.857	0.803	0.911	0.656	0.987	4.725	0.032	150.000	34.545	651.330
Male, < 65 years	439	173	211	35	20	0.896	0.858	0.832	0.913	0.875	0.440	0.886	0.853	0.920	0.795	0.931	6.300	0.121	52.147	29.051	93.605
Male, 65+ years	247	132	83	21	11	0.923	0.798	0.863	0.883	0.870	0.579	0.865	0.814	0.915	0.896	0.846	4.571	0.096	47.429	21.754	103.407
No Revasc	827	351	367	74	35	0.909	0.832	0.826	0.913	0.868	0.467	0.873	0.847	0.899	0.806	0.923	5.419	0.109	49.736	32.423	76.295
PCI	188	47	120	15	6	0.887	0.889	0.758	0.952	0.888	0.282	0.894	0.841	0.947	0.552	0.981	7.981	0.127	62.667	22.938	171.205
CABG	61	28	28	5	0	1.000	0.848	0.848	1.000	0.918	0.459	0.902	0.814	0.989	0.826	1.000	6.600	0.000	NaN	NaN	NaN
Revasc of any type	249	75	148	20	6	0.926	0.881	0.789	0.961	0.896	0.325	0.902	0.860	0.944	0.644	0.981	7.778	0.084	92.500	35.642	240.058