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Sirius red staining (objective magnification 10×). (a) Control mice for CCl4 and sham-operated mice did not develop fibrosis (Stage 0 or F0). (b) CCl4 mice developed micronodular cirrhosis (Stage IV) after 16 weeks of CCl4 administration (black arrow: fibrotic strands). (c) Six weeks after CBDL induction, mice developed fibrosis with nodule formation (F4) (black arrow: fibrotic strands).
