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. 2009 Feb;90(1):79–94. doi: 10.1111/j.1365-2613.2008.00618.x

Table 2.

Percentage of prostatic tissue compartments in control and treated animals of different postnatal developmental ages (mean ± SE)

Tissues

Epithelium Lumen Smooth muscle cell (SMC) Fibrovascular stroma




Exp. groups Post -treatment periods Young Adult Old Young Adult Old Young Adult Old Young Adult Old
Control 1 22.2 ± 0.71 18.8 ± 0.9a,1 26.1 ± 1.1a,1 19.6 ± 1.7a,1 49.9 ± 2.3a 39.4 ± 1.7a 26.0 ± 0.8a,1 12.8 ± 0.7a 10.4 ± 0.4a,1 32.2 ± 1.6a,1 19.0 ± 1.5a 23.6 ± 0.91
7 18.2 ± 0.7a,2 16.7 ± 0.7a,1,2 24.5 ± 0.91 26.8 ± 2.3a,1 49.5 ± 2.3a 42.9 ± 1.2a 23.6 ± 1.2a,1 11.8 ± 0.6a 13.7 ± 0.5a,2 31.2 ± 1.6a 22.0 ± 1.7a 18.8 ± 0.9a,2
14 18.9 ± 0.82 20.4 ± 1.3a,1 23.3 ± 0.91 34.4 ± 2.6a,2 50.9 ± 2.9a 40.8 ± 1.5a 20.2 ± 1.1a,2 12.1 ± 1.0a 13.9 ± 0.6a,2 26.5 ± 1.6 16.9 ± 1.4a 21.9 ± 0.9a,1
21 21.3 ± 1.0a,1 22.0 ± 0.9a,1,3 22.1 ± 1.1a,2 21.3 ± 2.11 48.9 ± 2.0a 39.1 ± 1.9a 29.5 ± 1.3a,1,2 11.6 ± 0.6a 14.1 ± 0.7a,2 27.8 ± 1.5a 17.4 ± 1.2a 24.3 ± 1.01
Finasteride 1 19.9 ± 0.91 19.6 ± 0.8a,1 25.5 ± 0.7a 40.8 ± 1.5b,1 44.2 ± 2.1a,1 29.3 ± 1.6b,1 19.9 ± 0.8b,1 14.2 ± 0.9a,c,1 16.6 ± 0.7b 19.4 ± 1.3b,1 22.3 ± 1.7a,b 28.5 ± 1.31
7 20.1 ± 1.1a,b,1 26.3 ± 1.2b,2 23.6 ± 0.8 34.2 ± 2.2a,1 36.7 ± 2.4b,1 35.0 ± 1.4b,2 21.0 ± 1.3a,1 12.6 ± 0.6a,b 16.8 ± 0.4b 24.6 ± 1.3a,b,1 24.4 ± 1.6a 24.8 ± 1.3b,1
14 21.7 ± 0.81,2 18.8 ± 0.7a,1 24.4 ± 0.9 18.0 ± 1.5b,2 45.2 ± 1.9a,1 34.7 ± 1.2b,2 27.9 ± 0.9b,2 9.9 ± 0.7a,b,2 16.8 ± 0.4b 32.2 ± 1.52 26.0 ± 1.8b 23.9 ± 1.3a,b,2
21 18.2 ± 0.9a,1,3 24.7 ± 0.9a,2 26.9 ± 1.1b 20.2 ± 1.92 29.2 ± 2.6b,2 33.8 ± 1.1a,b,1 25.1 ± 1.3b,2 21.1 ± 7.1b,3 17.7 ± 0.6b 36.4 ± 1.6a,2 23.8 ± 8.1b 21.6 ± 0.92
Letrozol 1 23.0 ± 0.91 14.5 ± 0.9b,1 19.0 ± 1.0b,1 27.5 ± 2.3c,1 61.9 ± 1.7b,1 38.1 ± 2.3a 22.5 ± 1.1b 8.8 ± 0.3b,1 16.4 ± 0.8b,1 26.9 ± 1.5a,1 14.8 ± 1.0a,1 26.5 ± 1.61
7 22.5 ± 0.9b,1 19.0 ± 0.8a,2 22.9 ± 1.12 28.2 ± 2.6a,1 54.3 ± 2.2a,2 36.2 ± 1.6b 19.1 ± 0.9b 9.6 ± 0.7a,1 13.6 ± 0.6a,2 30.2 ± 2.0a,1 16.7 ± 1.3b,1 27.4 ± 1.0b,c,1
14 19.6 ± 0.92 20.9 ± 0.8a,3 21.8 ± 1.11 32.1 ± 1.8a,1,2 47.2 ± 1.7a,3 43.1 ± 1.7a 18.7 ± 1.0a 11.9 ± 0.7a,2 13.6 ± 0.6a,2 29.5 ± 1.71 19.8 ± 1.1a,2 21.6 ± 0.8a,2
21 20.4 ± 0.8a,1 22.9 ± 0.6a,3 21.2 ± 0.8a,1 22.3 ± 1.91,3 44.5 ± 1.7a,3 41.8 ± 1.8a,c 21.9 ± 1.3b 13.2 ± 0.7a,2 15.3 ± 0.8a,1 35.3 ± 2.1b,2 19.0 ± 1.3a,1 21.6 ± 1.02
Fin + Let 1 21.5 ± 0.81 20.8 ± 0.7a,1 21.5 ± 0.9b 25.4 ± 1.1a,c,1 38.7 ± 1.6b,1 32.7 ± 1.8a,b,1 24.7 ± 0.9a,1 16.3 ± 1.0c,1 18.3 ± 0.8a,1 28.3 ± 1.5a,1 24.2 ± 1.1b 28.2 ± 1.41
7 23.5 ± 1.2b,1 24.4 ± 0.8b,1 22.9 ± 0.8 11.9 ± 1.9b,2 35.0 ± 1.7b,1 29.2 ± 1.3c,1 28.3 ± 1.1c,1 14.6 ± 0.7b,1,2 17.1 ± 0.6a,c,2 36.6 ± 2.3a,c,2 25.9 ± 1.0a 30.5 ± 1.1c,1
14 21.8 ± 0.91 28.7 ± 0.7b,2 23.4 ± 0.7 16.2 ± 1.9b,3 31.2 ± 1.2b,2 34.3 ± 1.6b,1 31.4 ± 1.6b,2 14.0 ± 0.6a,c,1,2 15.6 ± 0.61 30.6 ± 1.41 26.1 ± 1.1b 26.6 ± 1.4b,1
21 16.3 ± 0.8b,2 28.3 ± 0.8b,2 22.3 ± 0.6a 18.0 ± 1.33 31.1 ± 1.3b,2 40.4 ± 1.2a,c,2 24.5 ± 1.1b,1 18.3 ± 0.9b,1,3 14.1 ± 0.5a,2 41.1 ± 1.5b,2 22.5 ± 0.7b 23.2 ± 1.42

Statistical analysis were based on anova and Tukey tests.

Alphabetic superindices (a, b, c) indicate statistically significant inter-group differences, when comparing treatment kind; numeric superindices (1, 2, 3) indicate statistically differences inter-group differences, when comparing stages of post-treatment period. Significant P ≤ 0.05. Comparisons among different postnatal ages where not executed.