. Author manuscript; available in PMC: 2009 May 1.

Published in final edited form as: Neuropsychopharmacology. 2008 Aug 13;34(6):1395–1405. doi: 10.1038/npp.2008.131

Table 4.

Common candidates on the miRNA effector and BPD candidate gene lists

Symbol	Description	miRNAs (context score)			Genetics
		miR-128a	miR-24	miR-34a	p-value
CAPN6	Calpain 6			−0.26	9.99E-06
DPP10	Dipeptidyl-peptidase 10		−0.17		1.31E-05
ESRRG	Estrogen-related receptor gamma		−0.07		2.15E-04
FAM126A	Family with sequence similarity 126, member A.	−0.78			2.04E-05
GRM7	Metabotropic glutamate receptor 7			−0.30	9.73E-05
THRB	Thyroid hormone receptor, beta	−0.31			2.16E-04

The effectors of miRNAs targeted by both lithium and VPA treatments were predicted using TargetScan. Genetic data were originated from the WTCCC whole genome association study. The WTCCC-reported SNPs list (p-value < 0.001) was obtained from the supplement of the WTCCC paper and SNP corresponding gene IDs were retrieved from the NCBI database. Comparison of predicted miRNA effectors and genetic data was done using the Ingenuity Pathways Analysis System.