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. Author manuscript; available in PMC: 2009 Nov 15.
Published in final edited form as: Bioorg Med Chem Lett. 2008 Sep 9;18(22):6007–6011. doi: 10.1016/j.bmcl.2008.09.019

Table 4.

MIC testing of erythromycin analogs.

graphic file with name nihms79017f7.jpg
MIC (μg/mL)
Entry Compound R R′ R′′ S. aureus 29213 E. faecalis 29212
1 6 graphic file with name nihms79017t4.jpg graphic file with name nihms79017t4.jpg H 32 32
2 7 graphic file with name nihms79017t5.jpg graphic file with name nihms79017t5.jpg H 32 >32
3 8 graphic file with name nihms79017t6.jpg graphic file with name nihms79017t6.jpg H >32 >32
4 9 graphic file with name nihms79017t7.jpg graphic file with name nihms79017t7.jpg H >32 >32
5 10 graphic file with name nihms79017t4.jpg graphic file with name nihms79017t4.jpg P(O)(OPh)2 >32 >32
6 11 graphic file with name nihms79017t5.jpg graphic file with name nihms79017t5.jpg P(O)(OPh)2 >32 >32
7 12 graphic file with name nihms79017t6.jpg graphic file with name nihms79017t8.jpg P(O)(OPh)2 >32 >32
8 13 graphic file with name nihms79017t7.jpg graphic file with name nihms79017t7.jpg P(O)(OPh)2 >32 >32
9 14 graphic file with name nihms79017t6.jpg graphic file with name nihms79017t8.jpg H 32 >32
10 15 graphic file with name nihms79017t7.jpg H graphic file with name nihms79017t7.jpg >32 >32
11 16 graphic file with name nihms79017t4.jpg H H 16 32
12 17 graphic file with name nihms79017t5.jpg H H 16 32
13 18 graphic file with name nihms79017t6.jpg H H 32 >32
14 19 graphic file with name nihms79017t7.jpg H H 32 32
15 2 H H H 1 2