Table 1.
Cellular enrichment of gene transcripts | ||||
---|---|---|---|---|
# Genes | ~Neuronal (%) | Both (%) | ~Glial (%) | |
CC | 24* | 56* | 20* | |
‘Mood and therapeutic’ | 146 | 19 | 53 | 28 |
‘Therapeutic only’ | 238 | 21 | 59 | 20 |
AMY | 23* | 57* | 20* | |
‘Mood and therapeutic’ | 241 | 23 | 38 | 39 |
‘Therapeutic only’ | 82 | 46 | 37 | 17 |
DG | 23* | 53* | 24* | |
‘Mood and therapeutic’ | 62 | 23 | 48 | 29 |
‘Therapeutic only’ | 19 | 11 | 36 | 53 |
‘# genes’ indicates the number of genes identified in the respective category.
Italic values with (*) indicate expected proportions of glial- and neuronal-enriched genes (see Materials and methods). Gene categories are described in the text. Bold numbers represent values that are significantly different from expected proportions (χ2 tests, P<0.05 adjusted for multiple comparisons). Differences from expected proportions in ‘therapeutic only’ genes were not significant in DG, due to the low number of genes within that category.