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. Author manuscript; available in PMC: 2009 Dec 25.
Published in final edited form as: J Med Chem. 2008 Dec 25;51(24):7921–7932. doi: 10.1021/jm8010299

Figure 4.

Figure 4

Comparison of the top-scoring poses of the crystallographic type-II ligands in DOLPHIN MRC ensembles of their target kinases (red) with the crystallographic complexes (green). *For MK14 and compound 2 (PDB Het AQZ), the correct pose was ranked first after refinement and full-atom scoring.