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. Author manuscript; available in PMC: 2009 Dec 25.
Published in final edited form as: J Med Chem. 2008 Dec 25;51(24):7921–7932. doi: 10.1021/jm8010299

Figure 6.

Figure 6

Examples of compound secondary activity prediction using DOLPHIN screening. Top-scoring poses of the inhibitors in DOLPHIN models of the off-target kinases are shown. Inhibition of these kinases was confirmed by the authors of the original studies.