Table 2.
The intensity of HER-2/neu(C-ErbB-2) overexpression and histological characteristics
| Parameters | Total No. of patients | c-ErbB-2 protein overexpression intensity | P value | R test | |||
|---|---|---|---|---|---|---|---|
| 0 | 1+ | 2+ | 3+ | ||||
| Histological type | |||||||
| IDC | 61 | 9 | 12 | 20 | 20 | <0.05 | |
| ILC | 8 | 3 | 4 | 1 | 0 | ||
| IDC+DCIS | 18 | 0 | 1 | 10 | 7 | ||
| IDC+ Paget's | 3 | 0 | 0 | 0 | 3 | ||
| Grade | |||||||
| I | 2 | 0 | 2 | 0 | 0 | <0.05 | 0.94 |
| II | 17 | 3 | 2 | 6 | 6 | ||
| III | 71 | 4 | 18 | 24 | 25 | ||
| Tumor stage | |||||||
| Stage I | 5 | 2 | 1 | 1 | 1 | >0.05 | |
| Stage II | 23 | 0 | 5 | 9 | 9 | ||
| Stage III | 41 | 3 | 10 | 16 | 12 | ||
| Stage IV | 3 | 0 | 2 | 1 | 0 | ||
| Tumor recurrence | |||||||
| Recurrent | 29 | 1 | 3 | 12 | 13 | >0.05 | |
| Primary | 61 | 11 | 14 | 19 | 17 | ||