Table 1. Substrate-Specificity of pfHDAC-1.
| substrate | Kmapp (μM) | kcat (s−1) |
|---|---|---|
| Ac-Leu-Gly-Lys(Ac)-AMC 1 | 30 ± 2 | 0.19 ± 0.01 |
| Boc-Lys(trifluoroacetyl)-AMC 2 | NAa | NA |
a
No activity observed with 2 in the presence of excess substrate and pfHDAC-1.
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